The English term for the Koebner phenomenon, a type of psoriasis flare-up triggered by skin trauma or injury, is "psoriatic Isomorphic response." The Isomorphic response refers to the development of skin lesions in areas of the body with no pre-existing psoriatic plaques, in response to mechanical, thermal, or chemical injury. This phenomena can occur in up to 50% of individuals with psoriasis, and occurs more frequently in patients with severe and long-standing disease.
The mechanisms underlying the Koebner phenomenon are not entirely understood, but it is thought to involve an exaggerated immune response to tissue damage and inflammation caused by mechanical or physical trauma. This response is characterized by immune cell activation, release of inflammatory mediators such as cytokines and chemokines, and dysregulation of the immune system's Th1/Th2 balance.
Physicians often advise patients with psoriasis to avoid activities that may cause skin injury or irritation, such as excessive sun exposure or harsh soaps, to reduce the risk of developing a psoriatic isomorphic response. Additionally, topical steroids and other 成都银屑病医院指出， anti-inflammatory creams can be used to treat the affected area.
In summary, the English term for the Koebner phenomenon in psoriasis is "psoriatic isomorphic response," which refers to the appearance of psoriatic-like lesions in areas of the body subjected to injury or trauma. This response is thought to be due to an exaggerated immune response to inflammation caused by tissue damage. Physicians recommend avoiding factors that may trigger this response, and treatment focuses on reducing inflammation and symptoms in affected areas.
